Table 3.
Relationship Between Changes in microCT Variables and Histomorphometric Cancellous Bone Formation (MS/BS)
| Change in microCT variable |
Predicted by change in MS/BS (%) |
p | |
|---|---|---|---|
|
1yr PTH(1–84) treatment |
BV/TV (%) | 0.62 | 0.03 |
| BS/TV (mm2/mm3) | 0.70 | 0.01 | |
| BS/BV (mm2/mm3) | −0.43 | 0.17 | |
| Tb.Th (mm) | 0.23 | 0.47 | |
| Tb.Sp (mm) | −0.68 | 0.01 | |
| Tb. SD (1) | 0.31 | 0.36 | |
| Tb.N (mm−1) | 0.69 | 0.01 | |
| SMI (1) | −0.57 | 0.05 | |
| Conn.D /mm3 | 0.68 | 0.02 | |
| Force (N) | 0.37 | 0.29 | |
| Young’s modulus (N/mm2) |
0.39 | 0.26 | |
|
2yr PTH(1–84) treatment |
BV/TV (%) | 0.23 | 0.42 |
| BS/TV (mm2/mm3) | 0.24 | 0.40 | |
| BS/BV (mm2/mm3) | −0.28 | 0.31 | |
| Tb.Th (mm) | 0.12 | 0.66 | |
| Tb.Sp (mm) | −0.29 | 0.30 | |
| Tb. SD (1) | −0.02 | 0.94 | |
| Tb.N (mm−1) | 0.28 | 0.30 | |
| SMI (1) | −0.36 | 0.18 | |
| Conn.D (/mm3) | 0.22 | 0.43 | |
| Force (N) | 0.39 | 0.19 | |
| Young’s modulus (N/mm2) |
0.40 | 0.18 |