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. Author manuscript; available in PMC: 2017 May 15.
Published in final edited form as: J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Nov 27;1021:188–196. doi: 10.1016/j.jchromb.2015.11.021

Figure 5.

Figure 5

Correlation of log[(specific retention factor)/protein content] versus the logarithm of the binding constants that have been reported for various drugs with AGP (■) or HSA (◆). The equation for the best-fit line was y = [1.08 (± 0.19)] x − [5.55 (± 0.40)], with a correlation coefficient of 0.9057 (n = 9). If a drug had a range of binding constants listed in Table 3 at pH 7.4 and 37 °C, the average of that range was used in this plot. If values were listed for the drug in Table 3 at various temperatures, the value that corresponded to 37 °C or the closest temperature to 37°C was used to construct this plot.