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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: J Bone Miner Res. 2016 Jan 6;31(5):994–1002. doi: 10.1002/jbmr.2760

Table 1.

QTL Identified for Ca Absorption, BMD, and BMC

QTL ID Chr High Allele Peak estimate (cM)1 1-LOD CI (cM)2 1- LOD CI (Mb)2 CaAbs3 BMD BMC (r2)4
0.50% 0.25% RCR 0.50% 0.25% RCR 0.50% 0.25% RCR
QTL1a 1 DBA 68.4 66.8–69.03 155.5–159.4 4.8 5 0.21
QTL1b* 1 B6 88.3 87.9–91.7 183.8–187.6 3.9 4.9 0.17; 0.2
DBA 90.6 2.4 0.06
QTL2* 2 B6 21.0 20.6–21.6 29.4–30.4 6.1 0.28
QTL3* 3 B6 29.6 27.9–31.7 57.6–68.4 5.6 0.24
DBA 30.2 2.2 0.07
QTL4* 4 B6 45.8 44.8–50.7 96.8–108.9 3.2 4.8 0.13; 0.21
DBA 49.2 8 4.4 0.27; 0.19
QTL7 7 DBA 29.9 23.9–33.2 37.1–54.5 2.2 0.07
B6 30.3 4.4 0.13
QTL8a 8 B6 23.7 22.7–26.9 36.3–47.7 4.7 0.19
QTL8b* 8 DBA 28.6–31.6 26.9–32.7 47.7–65.3 6 3.6 0.186; 0.16
QTL9a 9 DBA 43.7 43.1–44.7 77.4–81.8 3.7 0.15
QTL9b 9 DBA 58.3 57–59.74 105.7–109.8 2.8 4.5 0.12; 0.19
QTL10 10 B6 62.8–67.8 61.7–68.1 114.5–120.3 4 2.5 0.11; 0.1
QTL12 12 DBA 6.9–8.8 5.2–12.2 10.4–29.7 2 3.8 0.04; 0.16
QTL14 14 DBA 21.1 20.7–23.3 33.9–45.6 4.1 0.18
QTL15a* 15 B6 15.1–17.7 13.6–24 32.4–57.5 3.3 4.2 6.4 0.13; 0.18; 0.28
QTL15b* 15 B6 32.3–36 30.87–37.6 69.2–78.8 5.1 2.2 0.22; 0.067
1

QTL within 5 cM (centimorgans) were reported together.

2

1-LOD confidence intervals in cM or Mb (Build GRCm38).

3

Abbreviations: CaAbs (Ca absorption), BMD (Bone Mineral Density), BMC (Bone Mineral Content); 0.50% and 0.25% are dietary Ca levels, RCR (Response to dietary Ca restriction).

4

(r2) = proportion of the phenotype variance explained by the QTL. If more than one QTL is within a loci the r2 values are reported in order of phenotype and diet,

5

LOD scores for each loci. LOD > 2 but under the permutation threshold = putative peak (highlighted).

*

Loci selected for in depth characterization.