Table 3.
Baseline and angiographic characteristics of lesions approached with antegrade-only techniques, classified according to use of antegrade dissection re-entry.
| Variable | Overall | Antegrade Dissection Re-entry |
AWE-only | |
|---|---|---|---|---|
| Clinical Characteristics | n=767 | n=248 | n=519 | p |
| Age (years)* | 65.1±10.3 | 64.6±9.8 | 65.4±10.5 | 0.35 |
| Men (%) | 81.6 | 86.4 | 79.3 | 0.019 |
| Hypertension (%) | 89.7 | 91.6 | 88.9 | 0.25 |
| Hyperlipidemia (%) | 94.2 | 95 | 93.9 | 0.53 |
| Diabetes mellitus (%) | 45.8 | 46.7 | 45.4 | 0.75 |
| Smoking (%) | 29.6 | 32.1 | 28.5 | 0.002 |
| Heart failure (%) | 25.1 | 28.6 | 23.4 | 0.13 |
| History of MI (%) | 40 | 42.3 | 38.9 | 0.38 |
| History of CABG (%) | 24.4 | 31.3 | 21.1 | 0.003 |
| History of stroke (%) | 10.4 | 10.5 | 10.4 | 0.97 |
| Prior PCI (%) | 61 | 63.3 | 59.9 | 0.37 |
| Prior CTO PCI failure (%) | 15.6 | 20.1 | 13.1 | 0.015 |
| Peripheral arterial disease (%) |
14.1 | 17.1 | 12.7 | 0.11 |
| Angiographic Characteristics | n=767 | n=248 | n=519 | p |
| CTO target vessel | 0.23 | |||
| RCA (%) | 48.8 | 53.4 | 46.7 | |
| LCX (%) | 21.7 | 19.3 | 22.85 | |
| LAD (%) | 29.4 | 27.3 | 30.5 | |
| CTO length (mm)* | 28(16-38) | 30 (22-40) | 23 (15-34) | <0.001 |
| Interventional collaterals (%) |
45.6 | 44.1 | 46.4 | 0.62 |
| Moderate/severe calcification (%) |
49.1 | 50.2 | 48.5 | 0.67 |
| Moderate/severe tortuosity (%) |
30.7 | 35.2 | 28.3 | 0.06 |
| Proximal cap ambiguity (%) |
18.5 | 20.1 | 17.6 | 0.48 |
| In-stent restenosis (%) | 14.5 | 15.8 | 13.8 | 0.49 |
| J-CTO score* | 2.1±1.2 | 2.5±1.1 | 1.9±1.2 | <0.001 |
| PROGRESS CTO score* | 1.3±1.1 | 1.3±1.1 | 1.2±1.1 | 0.24 |
CABG, coronary artery bypass graft surgery; IVUS, intravascular ultrasound; LVAD, left ventricular assist device; MACE, major adverse cardiovascular events; PCI, percutaneous coronary intervention
*
mean±standard deviation or median (interquartile range).