Figure 5.
FTIRI variables in cortical bone of Tibia (Top) and L3 Vertebrae (Bottom). There were no cortices on the 10-day-old vertebrae. Min/mat = mineral-to-matrix peak area ratio; C:P = carbonate-to-phosphate peak area ratio; XST= crystallinity intensity ratio; HPO4 = acid phosphate substitution (intensity ratio), XLR = collagen cross-link (intensity) ratio. Bar colors: black – Col1a2+/+; light grey Col1a2+/G610C. All values are mean ± SD, * p<0.05 relative to same bone type, same age, different genotype, based on GEE model; # p<0.05 10 days vs. 2 months, same bone, same genotype GEE model.