Table 1.

Parameters of surface electrocardiography (ECG) in age-matched (20 weeks old) Clcn3^+/+ mice¹ and hsCLC-3^OE mice² under control and myocardial ischemia and reperfusion conditions.

	Clcn3+/+ (n=8)			hsCLC-3OE (n=6)
	Control	Ischemia	Reperfusion	Control	Ischemia	Reperfusion
ECG (Lead I)
HR (bpm)	400.9±0.9	379.3±7.4	293.2±16.3	403.4±1.5	427.10±20.6	338.6±45.2
P (ms)	11.3±0.7	11.1±0.7	13.1±0.6	10.2±0.5	8.7±0.8	10.0±0.8*
PR(ms)	46.0±1.7	52.0±3.7	69.3±3.2†††, ‡	43.5±0.9	42.2±2.0	48.6±1.8**, †
R-R (ms)	149.7±0.4	158.6±3.1	206.5±11.1	148.7±0.5	142.2±7.1	185.9±22.1
QRS(ms)	11.3±0.3	13.5±1.6	14.0±1.0††	10.2±0.6	12.3±1.2	11.5±0.8
QT (ms)	26.5±1.2	62.4±2.9†††	33.6±1.1††, ‡‡‡	21.7±1.1*	45.9±4.6**, ††	23.2±1.4***, ‡‡
QTc (ms)	21.7±1.0	49.7±2.6†††	23.4±0.7‡‡‡	17.8±0.9*	38.5±3.9*, ††	17.1±0.7***, ‡‡

HR, heart rate; bpm, beats per minute (min).

¹Clcn3^+/+ mice: body weight 32.5±0.9 g;

²hsCLC-3^OE mice: body weight 29.80±2.38 g;

^*P<0.05,

^**P<0.01,

^***P<0.001vs Clcn3^+/+ group;

^†P<0.05,

^††P<0.01,

^†††P<0.001 vs control in the same group;

^‡P<0.05,

^‡‡P<0.01,

^‡‡‡P<0.001 vs ischemia in the same group