Table 2.
Ln(cortisol) on waking and waking plus 2.5, 8, and 12 h and bed time (diurnal slope) on recurrent short sleep and chronic insomnia symptoms.
N = 3,064 | Recurrent short sleep duration |
Chronic insomnia symptoms |
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---|---|---|---|---|---|---|---|---|
Model 1 |
Model 2 |
Model 1 |
Model 2 |
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β (SE) | P value | β (SE) | P value | β (SE) | P value | β (SE) | P value | |
Hours since waking | −0.141 (0.048) | 0.004 | −0.139 (0.048) | 0.004 | −0.149 (0.048) | 0.002 | −0.151 (0.048) | 0.002 |
Hours since waking squared | 0.005 (0.002) | 0.003 | 0.005 (0.002) | 0.003 | 0.005 (0.002) | 0.001 | 0.005 (0.002) | 0.001 |
Recurrent short sleep (frequency) | ||||||||
No occurrences of short sleep | REF | REF | ||||||
One occurrence | −0.029 (0.035) | 0.411 | −0.017 (0.036) | 0.635 | ||||
Two occurrences | −0.108 (0.056) | 0.052 | −0.094 (0.056) | 0.088 | ||||
Three occurrences | −0.190 (0.063) | 0.003 | −0.163 (0.064) | 0.010 | ||||
Interaction: hrs since waking × short sleep | ||||||||
No occurrences of short sleep | REF | REF | ||||||
One occurrence × hours since wakinga | 0.009 (0.004) | 0.015 | 0.009 (0.004) | 0.015 | ||||
Two occurrences × hours since wakingb | 0.014 (0.006) | 0.014 | 0.014 (0.006) | 0.014 | ||||
Three occurrences × hours since wakingc | 0.020 (0.006) | 0.002 | 0.020 (0.006) | 0.002 | ||||
Chronic insomnia symptoms (frequency) | ||||||||
No occurrences of insomnia symptomsd | REF | REF | ||||||
One occurrence | 0.003 (0.026) | 0.912 | 0.004 (0.026) | 0.884 | ||||
Two occurrences | −0.015 (0.032) | 0.628 | −0.020 (0.033) | 0.548 | ||||
Three occurrences | −0.052 (0.036) | 0.154 | −0.060 (0.039) | 0.123 | ||||
Interaction: hrs since waking × insomnia symptoms | ||||||||
No occurrences of insomnia symptoms | REF | REF | ||||||
One occurrence × hours since wakinge | −0.001 (0.003) | 0.802 | −0.001 (0.003) | 0.801 | ||||
Two occurrences × hours since wakingf | −0.003 (0.003) | 0.322 | −0.003 (0.003) | 0.320 | ||||
Three occurrences × hours since wakingg | 0.002 (0.004) | 0.553 | 0.002 (0.004) | 0.552 |
Model 1: recurrent short sleep (frequency) adjusted for cortisol sample number (dummy variables for whether the cortisol came from first/third/fourth/fifth/sixth sample—estimates of these, compared to the first sample are, −0.17, −0.20, −0.66 and −0.98 respectively) + waking time, stress of day of sampling. Model 2: Model 1 + age, sex, employment grade, smoking, alcohol intake, SF-36 Short Form Health Survey (physical and mental component scores), BMI (Body Mass Index), steroids, anti-depressants, sleeping drugs, +other sleep exposure.
P = 0.58 for one occurrence of short sleep × hours since waking × sex.
P = 0.61 for two occurrences of short sleep × hours since waking × sex.
P value = 0.86 three occurrences of short sleep × hours since waking × sex.
Insomnia symptoms: defined as number of times, across three time points, participant was in fourth quartile of reported insomnia symptom.
P = 0.71 for one occurrence of insomnia symptoms × hours since waking × sex.
P = 0.96 for two occurrences of insomnia symptoms × hours since waking × sex.
P value = 0.44 three occurrences of insomnia symptoms × hours since waking × sex.