Table 1. Characteristics of Pregnant Patients With IBD Included in the Study.
| Variable | Bio- IM- a (n=31) | Bio onlyb (n=24) | IM onlyc (n=7) | Bio and IMd (n=10) | P-valuee |
|---|---|---|---|---|---|
| UC/UC+CD | 26/31 (83.9) | 0/24 (0) | 3/7 (42.9) | 4/10 (40.0) | <0.001 |
| Age | 30.0 | 30.9 | 30.7 | 31.9 | 0.269 |
| Duration of disease (median) (yr) | 7.0 | 6.0 | 5.0 | 11.5 | 0.426 |
| Smoking | 0/31 (0) | 4/24 (16.7) | 2/7 (28.6) | 1/10 (10.0) | 0.022 |
| Drinking | 0/31 (0) | 2/24 (8.3) | 0/7 (0) | 0/10 (0) | 0.406 |
Values are presented as n (%).
aPregnancies received neither anti-TNF or thiopurine therapy.
bPregnancies received anti-TNF therapy only.
cPregnancies received thiopurine therapy only.
dPregnancies received both anti-TNF and thiopurine therapy.
eFisher's exact method for categorical variables and Kruskal Wallis test for continuous variables.
Bio, biologics; IM, immunomodulator.