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. 2016 May 11;6:25729. doi: 10.1038/srep25729

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Copyright © 2016, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Nine proteins were subjected to interaction studies against the CRE sequence using the catRAPID graphics tool. Aminoacid-nucleotide interactions for the whole protein and RNA sequences are represented as heat-maps that show interacting score values between −3 and +3. The strongest interacting regions correspond to the red areas; blue areas represent pairs showing weak aminoacid-nucleotide interaction. The CRE regions corresponding to nucleotides with high interaction values are highlighted in red in the chart on the right.