Table 2. Serum steroid levels.
Male Controls (n = 12) | Female Controls (n = 16) | Male Depression (n = 10) | Female Depression (n = 13) | Kruskal–Wallis test | Dunn’s test | |
---|---|---|---|---|---|---|
E2 (pg/mL) | 15.87 ± 5.56 | 2.24 ± 1.39 | 21.23 ± 8.20 | 2.08 ± 1.36 | H = 18.80df = 3p = 1.87 × 10−7 | M/C vs. F/C (p < 0.01) |
M/D vs. F/D (p < 0.001) | ||||||
DHEA (ng/mL) | 1.87 ± 0.65 | 2.24 ± 0.83 | 1.36 ± 0.45 | 1.50 ± 1.29 | H = 9.18df = 3p = 0.003 | F/C vs. F/D (p < 0.001) |
7α-OH-DHEA (pg/mL) | 147.92 ± 67.59 | 133.31 ± 40.65 | 113.06 ± 54.28 | 116.87 ± 83.76 | H = 2.81df = 3p = 0.203 | |
3β Adiol (pg/mL) | 25.08 ± 20.06 | 5.69 ± 7.31 | 22.23 ± 10.22 | 3.52 ± 3.41 | H = 20.03df = 3p = 1.11 × 10−6 | M/C vs. F/C (p < 0.01)M/D vs. F/D (p < 0.001) |
Δ5-diol (ng/mL) | 0.50 ± 0.31 | 0.23 ± 0.07 | 0.47 ± 0.18 | 0.16 ± 0.13 | H = 19.15df = 3p = 1.67 × 10−5 | M/C vs. F/C (p < 0.001)M/D vs. F/D (p < 0.05) |
F (ng/mL) | 103.30 ± 40.99 | 82.22 ± 26.87 | 106.96 ± 32.10 | 72.08 ± 19.59 | H = 6.19df = 3p = 0.025 | M/D vs. F/D (p < 0.05) |
The values are shown as mean ± standard deviation. Four group mean comparisons of serum levels of each steroid were performed. Abbreviations: 3β Adiol, 5α-androstane-3β,17β-diol; 7α-OH-DHEA, 7α-hydroxydehydroepiandrosterone; Δ5-diol, Androstenediol; DHEA dehydroepiandrosterone; E2, 17β-estradiol; F, cortisol; F/C, female controls; F/D, female depression group; M/C, male controls; M/D, male depression group.