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Thioredoxin reductase activity in 4a, 4b, 5a, or 5b treated PC3 cells: (A) activity of endogenous PC3 thioredoxin reductase from soluble whole cell lysates following incubation with 30 μM of 4a or 4b for 5 and 24 h (values normalized against DMSO control); (B) activity of endogenous PC3 thioredoxin reductase from soluble whole cell lysates following incubation with 5 μM of 5a or 5b for 5 h and 24 h (values normalized against DMSO control).
