Figure 3. Effect of YidC depletion on proteome profile of Mtb.

(a,c) Functional categories of proteins differentially expressed in yidC(−). YidC depletion results in upregulation of 71 (a,b) and downregulation of 100 proteins (c,d) by 1.3-fold or more. (b,d) Heat map represents upregulated (b) and downregulated (d) proteins that are grouped on the basis of assigned functions. Color intensities in the heat map represent levels of expression. Expression values from two independent experiments (Exp 1 and Exp 2) are shown in (b,d). All detected and identified proteins are listed in Supplementary Data 2.