Table 3.
Correlations among PASI score and study variable in psoriatic patients
Parameters | Simple correlation | Adjusted for BMI | ||
---|---|---|---|---|
PASI score | PASI score | |||
r | p value | r | p value | |
Age (years) | 0.129 | 0.083 | 0.147 | 0.057 |
DLQI | 0.632 | <0.001 | 0.612 | <0.001 |
Anthropometric variables | ||||
BMI (kg/m2) | 0.306 | <0.001 | – | – |
WC (cm) | 0.405 | <0.001 | 0.272 | <0.001 |
Metabolic profile | ||||
SBP (mmHg) | 0.219 | 0.003 | 0.162 | 0.036 |
DBP (mmHg) | 0.177 | 0.017 | 0.110 | 0.153 |
Glucose (mg/dl) | 0.181 | 0.015 | 0.109 | 0.158 |
Total cholesterol (mg/dl) | 0.398 | <0.001 | 0.499 | <0.001 |
HDL cholesterol (mg/dl) | −0.368 | <0.001 | −0.339 | <0.001 |
LDL cholesterol (mg/dl) | 0.489 | <0.001 | 0.462 | <0.001 |
Triglycerides (mg/ml) | 0.503 | <0.001 | 0.474 | <0.001 |
AST (U/l) | 0.203 | 0.006 | 0.131 | 0.089 |
ALT (U/l) | 0.184 | 0.014 | 0.096 | 0.215 |
MetS (n. parameters) | 0.450 | <0.001 | 0.362 | <0.001 |
CRP levels (ng/ml) | 0.430 | <0.001 | 0.383 | <0.001 |
Bioelectrical variables | ||||
R (Ohm/m) | 0.312 | <0.001 | 0.414 | <0.001 |
Xc (Ohm/m) | −0.587 | <0.001 | −0.529 | <0.001 |
Simple and partial correlation among PASI score, age, DLQI, anthropometric variables, metabolic profile and bioelectrical variables. There was a significant positive correlation among PASI score and DLQI, BMI, WC, SBP, DBP, glucose, lipid and hepatic profile, MetS and R; moreover there was a significant negative association with HDL-cholesterol and Xc. After adjustment for BMI, the association among PASI score and DBP, glucose, AST and ALT, were lost
Correlations among variables were analyzed using Pearson r or Spearman’s rho correlation coefficients. A p value in italic denotes a significant difference (p < 0.05)
PASI psoriasis area and severity index, DLQI dermatology life quality index, BMI body mass index, WC waist circumference, SBP systolic blood pressure, DBP diastolic blood pressure, HDL high-density lipoprotein, LDL low-density lipoprotein, AST aspartate aminotransferase, ALT alanine aminotransferase, MetS metabolic syndrome, CRP c-reactive protein, R resistance, Xc reactance