Table 1.
No | Compound | Main functions | References |
---|---|---|---|
1 | α-naphthoflavone | Inhibits IL-1β production | Kobayashi et al62 |
Inhibits induction of IL-1β and CYP1A1 | Adachi et al66 | ||
2 | Resveratrol | Inhibits IL-1β and CYP1A1 | Casper et al82 |
Suppresses Th17 generation | Xuzhu et al83 | ||
Activates caspase-8 | Byun et al85 | ||
Activates caspase-3/-9 | Nakayama et al86 | ||
3 | GNF351 | Suppresses IL-1β production | Lahoti et al65 |
Decreases IL-1β-induced production of VEGF-A | Lahoti et al88 | ||
Reduces IL-1β-induced MMP-2 and MMP-9 | Lahoti et al65 | ||
4 | Plant-derived alkaloids | Inhibits dioxin-mediated CYP1A1 induction | El Gendy and El-Kadi98 |
El Gendy et al99 |
Abbreviations: Ahr, aryl hydrocarbon receptor; RA, rheumatoid arthritis; CYP1A1, cytochrome P450, family 1, subfamily A, polypeptide 1; VEGF, vascular endothelial growth factor; MMPs, matrix metalloproteinases.