Table 1.

Piracetam and cognitive function

Reference	Title	Main results	Study type	Patients randomized
Holinski et al18	Cerebroprotective effect of piracetam in patients undergoing open heart surgery	Piracetam has no cerebroprotective effects in patients undergoing open heart cardiopulmonary bypass surgery	Clinical trial, randomized, double-blind	88 patients
Malykh and Sadaie1	Piracetam and piracetam-like drugs: from basic science to novel clinical applications to central nervous system disorders	A neuroprotective effect of piracetam in treatment of cerebrovascular and cognitive disorders of traumatic origin	Review
Fesenko11	Piracetam improves children’s memory after general anesthesia	Intravenously administered piracetam reduces cognitive dysfunction produced by anesthesia	Clinical trial, randomized, double-blind	250 children
Holinski et al14	Cerebroprotective effect of piracetam in patients undergoing coronary artery bypass surgery	Piracetam has cerebroprotective effects in patients undergoing non-open heart cardiopulmonary bypass surgery	Clinical trial, randomized, double-blind	120 patients