Figure 4.

Cell death and morphology changes after BEZ235 and PTX treatment.

Notes: (A) White-field images of the cell death caused by PTX and BEZ235 treatment alone or combination treatment after 24 hours. The dead cells and decreased cell numbers were clear in treated groups compared to the controls. (B) Cell morphology changes after 2 hours treatment with PTX or BEZ235 or both. All images were taken using an Olympus IX51 fluorescent microscope at 100× magnification.

Abbreviations: NE, nanoemulsion; PTX, paclitaxel.