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. 2016 May 5;12:1085–1101. doi: 10.2147/NDT.S94158

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© 2016 Huss et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Proportion of participants with improved (%) CGI-I (scores of 1 or 2), at end point, by treatment in prior MPH or stimulant-naïve subgroups (LOCF; full-analysis set).

Notes: *P=0.005; **P<0.001 versus placebo; error bars represent 95% confidence intervals. Improved includes CGI-I categories “very much improved” and “much improved”.

Abbreviations: ATX, atomoxetine; CGI-I, Clinical Global Impression – Improvement scale; GXR, guanfacine extended release; LOCF, last observation carried forward; MPH, methylphenidate; RCT, randomized controlled trial; RWS, randomized-withdrawal study.