Table 1.
Summary of prior stimulant medications
| Prior ADHD medication used | RCT |
RWS |
|||
|---|---|---|---|---|---|
| Placebo (n=111) | GXR (n=114) | ATX (n=112) | Total (n=337) | GXR (n=503) | |
| Prior MPH use, n (%) | 48 (43.2) | 46 (40.4) | 48 (42.9) | 142 (42.1) | 224 (44.5) |
| MPH, n (%) | 45 (40.5) | 46 (40.4) | 47 (42.0) | 138 (40.9) | 205 (40.8) |
| Dexmethylphenidate, n (%) | 3 (2.7) | 0 | 1 (0.9) | 4 (1.2) | 19 (3.8) |
| Prior non-MPH use, n (%) | 8 (7.2) | 7 (6.1) | 6 (5.4) | 21 (6.2) | 72 (14.3) |
| Mixed amphetamine salts, n (%) | 3 (2.7) | 2 (1.7) | 3 (2.6) | 8 (2.4) | 30 (6.0) |
| Amphetamine, n (%) | 1 (0.9) | 0 | 2 (1.8) | 3 (0.9) | 1 (0.2) |
| Dextroamphetamine, n (%) | 1 (0.9) | 0 | 0 | 1 (0.3) | 2 (0.4) |
| Lisdexamfetamine, n (%) | 3 (2.7) | 5 (4.4) | 1 (0.9) | 9 (2.7) | 39 (7.7) |
Note: Prior stimulant medication as named by participants in the Prior Stimulant Medication Questionnaire.
Abbreviations: ADHD, attention-deficit/hyperactivity disorder; ATX, atomoxetine; GXR, guanfacine extended release; MPH, methylphenidate; RCT, randomized controlled trial; RWS, randomized-withdrawal study.