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. Author manuscript; available in PMC: 2016 Sep 10.
Published in final edited form as: Nature. 2016 Mar 10;531(7593):258–262. doi: 10.1038/nature17194

Figure 4. Binding site for trans-NED19.

Figure 4

Structural interactions between the TPC1 and NED19. (top) Surface rendering showing the location of the NED19 binding site. (bottom) Molecular details of the NED19 binding-pocket at the interface between PI, PII, and VSDII. Simulated-annealing omit density contoured at 1σ is shown for NED19 (red) and interacting side chains (blue).