Figure 4. Binding site for trans-NED19.
Structural interactions between the TPC1 and NED19. (top) Surface rendering showing the location of the NED19 binding site. (bottom) Molecular details of the NED19 binding-pocket at the interface between PI, PII, and VSDII. Simulated-annealing omit density contoured at 1σ is shown for NED19 (red) and interacting side chains (blue).