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. 2016 May 9;10:36. doi: 10.3389/fncir.2016.00036

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Copyright © 2016 Harrison, Pinto, Brock and Dan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Imaging neuronal activity during spontaneous behaviors. (A) Examples of neuronal activity in ChAT-, GAD2-, and VGLUT2-Cre mice. Behaviors (sitting, eating/grooming, moving or running) are indicated by shading. (B) Changes in activity in individual ROIs at the onset of each behavior. Black crosses signify mean ± SEM. F_genotype = 4.5, p = 0.01; F_behavior = 102.7, p < 0.01; F_interaction = 16.3, p < 0.01, 2-way ANOVA, n = 22 ChAT, 108 GAD2, 58 VGLUT2 cells. See also Movie S1. (C) Mean activity of all ROIs from each cell type, aligned by behavior onset.