Figure 8.

Role of p53 in TF3-induced apoptosis and G2 cell cycle arrest of A2780/CP70 cells. The quantification histograms are shown with error bars. Data represent means ± SD from three independent experiments. (A) The effects of TF3 on the protein expression of p53 determined by western blotting. Significant differences among the treatments are indicated by different letters (p<0.05). (B) The effects of p53 siRNA (50 nM) on the protein expression of procaspase-8, procaspase-9 and cyclin B1 determined by western blotting. ^*p<0.05, ^**p<0.01, compared with respective controls.