Table 3.
Results of whole brain‐ analysis—clusters of greater decline in cortical thickness with age in PAX6 subjects compared to controls while including intracranial volume as a covariate of no interest
| Cluster number (hemisphere) | Surface area size (mm2) | Talairach coordinates maximum vertex (x, y, z) | Clusterwise probability | Atlas location of maximum vertex |
|---|---|---|---|---|
| 1 (left) | 2564.12 | −36.8, −18.3, 64.5 | 0.00010 | Precentral |
| 2 (left) | 1630.18 | −38.1, 50.0, −3.4 | 0.01590 | Rostral middle frontal |
| 3 (left) | 967.01 | −41.3, −67.3, 27.3 | 0.00010 | Inferior parietal |
| 1 (right) | 2132.38 | 34.0, −71.1, 28.7 | 0.02300 | Inferior parietal |
| 2 (right) | 1325.30 | 24.8, 0.1, 46.0 | 0.00140 | Caudal middle frontal |
| 3 (right) | 956.65 | 46.9, −42.5, 37.6 | 0.00010 | Supramarginal |