Skip to main content
. 2016 May 6;95(18):e3559. doi: 10.1097/MD.0000000000003559

FIGURE 2.

FIGURE 2

Amitriptyline (AM) activates TrkA in DRG neurons. A, DRG culture was treated without AM, or with AM (0.5 and 10 μM) for 12 hours. qRT-PCR was conducted to compare mRNA levels of TrkA and TrkB (ΔP > 0.05, vs 0 μM AM). B, Western blot was conducted to compare protein levels of TrkA, phosphorylated TrkA (phosph-TrkA), TrkB, and phosphorylated TrkA (phosph-TrkA). DRG = dorsal root ganglion, qRT-PCR = quantitative real-time polymerase chain reaction, TrkA = tyrosine kinases receptor A, TrkB = tyrosine kinases receptor B.