Table 4. . Association between two cis-single nucleotide polymorphisms at the HIF3A locus (rs8102595, rs3826795) and birth weight.
Single nucleotide polymorphism | Est. | 95% CI | p-value |
---|---|---|---|
rs8102595 |
0.39 |
(-0.89, 1.7) |
0.55 |
rs3826795 | 0.059 | (-1.0, 1.2) | 0.92 |
Regression coefficients (Est.) and 95% CI are reported as percentage change in birth weight per copy of the effect allele. p-values are two-sided. Analysis was done by linear regression of log-transformed birth weight against each SNP (additive genetic model), adjusting for ethnicity and child sex. The effect allele of rs8102595 is G and the effect allele of rs3826795 is C.