Table 3.
Quality of bottle filling.
| Under-filled bottles | Over-filled bottles | ||||
|---|---|---|---|---|---|
| References | Threshold (mL) | Rate (%) | Threshold (mL) | Rate (%) | Country |
| Vitrat-Hincky et al., 2011 | < 8 | 65 | >10 | 13.0 | France |
| Willems et al., 2012a,b | < 8 | 26.2–36.0 | >12 | 7.6-12.8 | Belgium |
| van Ingen et al., 2013 | < 8 | 55.3 | – | – | The Nederlands |
| Coorevits and Van den Abeele, 2015 | < 8 | 28.0 | >12 | 23.2 | Belgium |
| Chang et al., 2015 | < 8 | 97.7 | >10 | 0.2 | South Korea |
| Lin et al., 2013 | < 7 | 28.3 | >10 | 13.3 | Taiwan |
| Mermel and Maki, 1993 | < 5 | 20 | – | – | USA |
| Chang et al., 2015 | < 3 | 48.4 | – | – | South Korea |
a
Data from 5 hospitals
b
Thresholds were defined as 2 mL below and above the recommended volume per vial.