Table 2.
Co-primary efficacy endpoint: success ratea (% IGA clear/almost clear, ITT)
| Success rate | ||
|---|---|---|
| 0.3 % A/BPO | Vehicle | |
| Week 1 | 1 | 0 |
| Week 2 | 3.0 | 0 |
| Week 4 | 4.3 | 1.5 |
| Week 8 | 13* | 3.1 |
| Week 12 | 33.7** | 11 |
A adapalene, BPO benzoyl peroxide, IGA Investigator’s Global Assessment, ITT intent to treat population
* p < 0.05 vs. vehicle
** p < 0.001 vs. vehicle
aMultiple imputation data; post hoc analysis performed prior to week 12