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. 2016 Jan 5;7(3):330–344. doi: 10.1002/jcsm.12078

Figure 4.

Figure 4

H19 is increased in low fat‐free mass index chronic obstructive pulmonary disease patients compared to normal fat‐free mass index chronic obstructive pulmonary disease patients and is associated with muscle mass and strength. The expression of H19 was determined by quantitative PCR in samples of quadriceps from the validation cohort of chronic obstructive pulmonary disease patients and controls as described in Methods. H19 not different between patient groups or controls (A). In patients H19 was correlated with fat‐free mass index (r = −0.385, P = 0.001, B) and with was correlated with quadriceps strength both voluntary (MVC, r = −0.44, P < 0.001, C) and involuntary (TwQ = −0.38 P = 0.002, D) measurements of strength. Patients are shown as grey circles controls as black circles.