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Combination treatment with PA and TOP inhibitors (Eto and Cpt) enhances cell death. (A and B) PI uptake assay for determination of cell death induced with combination treatments. NCI-H1299 (A) and A549 (B) cells were treated with PA, Eto, Cpt or both for 72 h. Representative data from experiments performed in triplicate are shown in each right panel.
