Figure 4.
Induction of apoptosis in J45.01 (A) and U937 (B) cell lines. Cells were exposed to single drug, or in combination, for 48 h and analyzed by Western blotting. (C) J45.01 cells were pre-exposed to 20 μM Z-VAD-FMK for 2 h prior to exposure to the indicated drug combinations, then analyzed by Western blotting after 48 h. Clad: cladribine; Gem: gemcitabine; Bu: busulfan; SAHA: suberoylanilide hydroxamic acid; Casp: caspase