Table 2. Statistical analysis between paired tumor and normal samples or male and female samples using t test in Fig 4.

miRNA	Tissues	The first/second	The first/third	The first/fourth
miR-30a	Female: LUSC-nt & LUSC-tn	t = 3.3228, P = 0.0031	t = 2.9598, P = 0.0072	t = 2.2636, P = 0.0338
	Male: LUSC-nt & LUSC-tn	t = 6.7896, P<0.0001	t = 5.4469, P<0.0001	t = 4.4999, P = 0.0002
	LUSC-nt: Female & male	t = -2.2102, P = 0.0378	t = -2.6317, P = 0.0152	t = -2.3787, P = 0.0265
	LUSC-tn: Female & male	t = 1.4378, P = 0.1646	t = 0.3988, P = 0.6939	t = 1.3850, P = 0.1799
miR-183	Female: LUSC-nt & LUSC-tn	t = -1.6891, P = 0.1053	t = -2.6513, P = 0.0146	t = -4.1722, P = 0.0004
	Male: LUSC-nt & LUSC-tn	t = -0.4891, P = 0.6296	t = -3.4908, P = 0.0021	t = -6.7018, P = 0.0001
	LUSC-nt: Female & male	t = 0.8350, P = 0.4127	t = -0.3776, P = 0.7093	t = -0.2330, P = 0.8179
	LUSC-tn: Female & male	t = 1.6558, P = 0.1119	t = -0.0634, P = 0.9500	t = -0.4613, P = 0.6491
miR-451	Female: THCA-nt & THCA-tn	t = -2.6401, P = 0.0153	t = -2.0416, P = 0.0540	t = -1.0727, P = 0.2956
	Male: THCA-nt & THCA-tn	t = -3.0656, P = 0.0057	t = -3.7824, P = 0.0010	t = -0.0637, P = 0.9498
	THCA-nt: Female & male	t = -1.4825, P = 0.1524	t = -1.4711, P = 0.1554	t = -2.1874, P = 0.0396
	THCA-tn: Female & male	t = -0.7010, P = 0.4910	t = -1.7565, P = 0.0936	t = -1.5505, P = 0.1360
miR-221	Female: THCA-nt & THCA-tn	t = -1.2174, P = 0.2384	t = -1.4958, P = 0.1511	t = 0.0682, P = 0.9463
	Male THCA-nt & THCA-tn	t = 0.7464, P = 0.4646	t = -0.1590, P = 0.8753	t = 1.0025, P = 0.3287
	THCA-nt: Female & male	t = 0.3472, P = 0.7317	t = 0.5005, P = 0.6217	t = 0.0353, P = 0.9722
	THCA-tn: Female & male	t = 2.4642, P = 0.0254	t = 1.5584, P = 0.1387	t = 0.9358, P = 0.3633