Table 1.
Clinical Features of Primary Glial and Neuronal Tumors of the Ovary or Peritoneum.
| PT | Age, yrs | Neuroectodermal tumor type, location | Other ovarian neoplasm | Surgery | Adjuvant therapy | Follow-up |
|---|---|---|---|---|---|---|
| Ependymal tumors | ||||||
| 1 | 35 | Ependymoma, surface of ovary and peritoneum | Unknown | RSO | Unknown | NA |
| 2 | 50 | Ependymoma, ovary and peritoneum | None | RSO, previous LSO and hysterectomy for fibroid | Yes, radiation | AWD, residual peritoneal and omental disease (CT scan), 59 months |
| 3 | 36 | Anaplastic ependymoma, broad ligament, ovary and peritoneum | None | TAH-BSO, OM | Yes, carboplatin and etoposide | AWD, persistent ependymoma, 9 months |
| 4 | 29 | Anaplastic ependymoma, ovary and peritoneum | None | BSO, OM | Yes, BEP | AWD, residual disease in abdomen and pelvis (CT scan), 4.5 months |
|
| ||||||
| Astrocytic tumors | ||||||
| 5 | 38 | Low-grade astrocytoma, omentum, peritoneum and etc. | Mixed germ cell tumor, immature teratoma and yolk sac tumor | TAH-BSO, OM | Yes, BEP, paclitaxel and carboplatin, bevacizumab | NA |
| 6 | 24 | Anaplastic astrocytoma/high-grade glioma, right ovary | Mature cystic teratoma | RSO | No | NED, 5 months |
| 7 | 17 | High-grade glioma/astrocytoma, right ovary | Immature teratoma, low-grade | RSO | No | NED, 8 months |
| 8 | 19 | High-grade glioma/astrocytoma, left ovary | Immature teratoma, high-grade | LSO | Yes, BEP | NED, 18 months |
| 9 | 9 | High-grade glioma/astrocytoma, right ovary | Immature teratoma, low-grade | Unknown | Unknown | NA |
| 10 | 10 | High-grade glioma/astrocytoma arising from gliomatosis peritonei | Immature teratoma, high-grade; gliomatosis peritonei | Cytoreductive surgery; previous history of LSO, OM | Yes, HIPEC and radiation (etoposide and cisplatin before the diagnosis of glioma) | AWD, residual tumor in the pelvis (CT scan), 4 months (10 months after the diagnosis of ovarian immature teratoma) |
|
| ||||||
| Neuronal tumors | ||||||
| 11 | 22 | Neurocytoma, low grade, arising in the background of mature teratoma component in the diaphragm | Mixed germ cell tumor (immature teratoma and yolk sac tumor) | RSO, OM | Yes, BEP chemotherapy | AWD, mature teratomas only, 12 months (20 months after the diagnosis of ovarian mixed germ cell tumor) |
Abbreviations: PT, patient; yrs, years; RSO, right salpingo-oophorectomy; NA, not available; LSO, left salpingo-oophorectomy; AWD, alive with disease; CT, computed tomography; TAH, total abdominal hysterectomy; BSO, bilateral salpingo-oophorectomy; OM, omentectomy; BEP, bleomycin, etoposide, cisplatin; NED, no evidence of disease; HIPEC, hyperthermic intraperitoneal chemotherapy.