Table 4.
Normalized mRNA expression in the tibiales anteriores of mice with one tibialis anterior electroporated with a GDF‐15 expression vector and the contralateral tibialis anterior electroporated with a control vector
Gene | cont (log normalized expression, AU) | SEM | GDF‐15 (log normalized expression, AU) | SEM | Paired t‐test |
---|---|---|---|---|---|
GDF‐15 | −2.68 | 0.12 | 0.62 | 0.11 | 0.002 |
atrogin | −0.42 | 0.06 | −0.54 | 0.06 | 0.109 |
murf | −0.77 | 0.05 | −0.87 | 0.04 | 0.151 |
myhc2a | −0.28 | 0.17 | −0.62 | 0.12 | 0.013 |
myhc2x | 2.20 | 0.06 | 2.25 | 0.06 | 0.699 |
myhc 2b | 1.60 | 0.07 | 1.42 | 0.08 | 0.144 |
myhc I | −1.80 | 0.16 | −1.94 | 0.18 | 0.484 |
cyr61 | −1.12 | 0.05 | −1.28 | 0.04 | 0.049 |
CTGF | −1.40 | 0.04 | −1.54 | 0.05 | 0.086 |
PAI‐1 | −2.29 | 0.14 | −2.32 | 0.07 | 0.867 |
GDF, growth differentiation factor.