Table 1.

Nervous tissue levels of ³H-Marizomib compared with blood in the Sprague-Dawley rats

Region/Time	2–30 min	1–8 h	24 h
Brain: cerebrum	31.33 ± 12.77	53.00 ± 5.70	51.00
Brain: cerebellum	35.00 ± 12.86	56.25 ± 3.04	58.00
Brain: medulla	24.67 ± 9.03	38.75 ± 3.28	40.00
All brain	30.33 ± 6.04	49.33 ± 3.17	49.67 ± 5.24
Peripheral nerves	17.33 ± 5.81	20.25 ± 3.64	21.00
Spinal cord	21.33 ± 6.94	32.75 ± 7.23	38.00
Kidney	320.7 ± 170.7	250.8 ± 6.59	178.00

Data expressed as percent blood levels (mean ± SEM).