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. 2015 Jun 4;7(2):181–192. doi: 10.1002/jcsm.12040

Figure 1.

Figure 1

Activation of UNC‐105 causes protein degradation in muscle. Synchronized young adults were used (t = 0 h), and all experiments repeated at least three times. (A) Representative stains for β‐galactosidase at t = 72 h post‐adulthood; scale bar represents 100 µm. (B) Representative western blots of β‐galactosidase in 30‐worm lysates. Arrows show β‐galactosidase fusion protein at 146 kD. Wild‐type controls are not included as unc‐105; let‐2 results are not significantly different from published wild‐type values.4, 8, 10, 13 (C) Kinetics of β‐galactosidase degradation, quantified from three independent western blots. * denotes P < 0.05; ** denotes P < 0.01; *** denotes P < 0.001 between unc‐105 and unc‐105; let‐2, two‐way repeated measures ANOVA with Bonferroni correction. (D) Representative stains for β‐galactosidase at t = 72 h post‐adulthood; scale bar represents 100 µm.