Table 2.
Distribution of vascular endothelial growth factor genotype and allele among stroke patients and controls in two single‐nucleotide polymorphisms
| Author | Sample size | +936C/T | −1154G/A | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| C | T | CC | CT | TT | HWE | G | A | GG | GA | AA | HWE | |||
| Rueda et al. (2005) | Case | 53 | – | – | – | – | – | 77 | 29 | 26 | 25 | 2 | ||
| Control | 226 | – | – | – | – | – | 320 | 132 | 118 | 84 | 24 | 0.13 | ||
| Liu et al. (2007) | Case | 155 | 90 | – | – | – | – | – | ||||||
| Control | 195 | 150 | – | – | – | – | – | |||||||
| Zhang et al. (2007) | Case | 1849 | – | – | – | – | – | 2018 | 1680 | 539 | 940 | 370 | ||
| Control | 1798 | – | – | – | – | – | 1937 | 1659 | 515 | 907 | 376 | 0.00 | ||
| Li et al. (2007) | Case | 200 | 285 | 115 | 125 | 35 | 40 | – | – | – | – | – | ||
| Control | 100 | 154 | 46 | 70 | 14 | 16 | 0.00 | – | – | – | – | – | ||
| Li et al. (2009) | Case | 150 | 190 | 110 | 51 | 88 | 11 | – | – | – | – | – | ||
| Control | 120 | 180 | 60 | 67 | 46 | 7 | 0.80 | – | – | – | – | – | ||
| Kim et al. (2011) | Case | 991 | 1604 | 378 | 642 | 320 | 29 | 1619 | 363 | 674 | 271 | 46 | ||
| Control | 494 | 824 | 164 | 344 | 136 | 14 | 0.89 | 815 | 173 | 339 | 137 | 18 | 0.37 | |
| Fu et al. (2011) | Case | 147 | 249 | 45 | 106 | 37 | 4 | 227 | 67 | 86 | 55 | 6 | ||
| Control | 131 | 218 | 44 | 90 | 38 | 3 | 0.66 | 194 | 68 | 69 | 56 | 6 | 0.20 | |
| Yu et al. (2012) | Case | 420 | 573 | 267 | 172 | 229 | 19 | – | ‐ | – | – | – | ||
| Control | 456 | 706 | 206 | 267 | 172 | 17 | 0.09 | – | – | – | – | – | ||
| Fontanella et al. (2013) | Case | 200 | 350 | 50 | 153 | 44 | 3 | – | – | – | – | – | ||
| Control | 200 | 348 | 52 | 151 | 46 | 3 | 0.81 | – | – | – | – | – | ||
| Zhang et al. (2014) | Case | 68 | 114 | 22 | 48 | 18 | 2 | – | – | – | – | – | ||
| Control | 118 | 196 | 40 | 81 | 34 | 3 | 0.80 | – | – | – | – | – | ||