Table 2.
List of measurements used and the results from the group-wise permutation test and correlations with a measure of consciousness response (CRS-R). All p-values, shown in parenthesis, have been False Discovery Rate adjusted for 31 multiple comparisons (30 tests in this table and one test for correlation between SC impairment and fiber length, shown in Fig. 5A) using the linear step-up procedure, see Appendix A.1 for details. The final column contains the 95% bias corrected and accelerated confidence interval (CI) for the correlations in the fourth column, calculated via bootstrapping (resampling with replacement).
List of measurements used and the results from the group-wise permutation test and correlations with a measure of consciousness response (CRS-R). All p-values, shown in parenthesis, have been False Discovery Rate adjusted for 31 multiple comparisons (30 tests in this table and one test for correlation between SC impairment and fiber length, shown in Fig. 5A) using the linear step-up procedure, see Appendix A.1 for details. The final column contains the 95% bias corrected and accelerated confidence interval (CI) for the correlations in the fourth column, calculated via bootstrapping (resampling with replacement).
| Measurement Type | Metric | Group-wise test: patients-healthy | Correlations with CRS-R | 95% CI of correlations with CRS-R |
|---|---|---|---|---|
| Structural network | Characteristic path length | 2.23 (0.10) | 0.095 (0.87) | [− 0.67. 1.00] |
| Efficiency | − 6.83 (2.5 × 10− 6)a | 0.40 (0.34) | [− 0.71. 0.81] | |
| Clustering coefficient | 0.14 (0.93) | − 0.26 (0.58) | [− 0.79. 0.51] | |
| Modularity | 5.72 (3.5 × 10− 5)a | − 0.58 (0.16) | [− 0.88. 0.13] | |
| Small world index | 1.78 (0.16) | − 0.045 (0.93) | [− 0.77. 0.79] | |
| Degree | − 5.57 (4.0 × 10− 5)a | 0.22 (0.64) | [− 0.67. 0.79] | |
| Functional network | Characteristic path length | − 2.80 (0.043)a | 0.44 (0.31) | [− 0.28. 0.97] |
| Efficiency | 1.95 (0.16) | − 0.42 (0.32) | [− 0.93. 0.36] | |
| Clustering coefficient | 2.40 (0.083) | − 0.59 (0.16) | [− 0.95. 0.22] | |
| Modularity | 0.68 (0.61) | − 0.19 (0.66) | [− 0.95. 0.48] | |
| Small world index | 3.06 (0.032)a | − 0.57 (0.16) | [− 0.96. 0.15] | |
| Un-normalized degree | − 2.68 (0.050)a | 0.48 (0.28) | [− 0.23. 0.95] | |
| Model parameters | Model propagation time | 1.36 (0.31) | 0.76 (0.043)a | [0.40. 0.95]b |
| Model correspondence | 0.0090 (0.99) | 0.42 (0.32) | [− 0.67. 0.86] | |
| z-Score of FC between region-pairs | Region-pairs w/intact SC | NA | 0.30 (0.58) | [− 0.97. 0.91] |
| Region-pairs w/impaired SC | NA | 0.67 (0.13) | [− 0.96. 0.91] |
Significant at level α = 0.05.
Bootstrapped 95% bias corrected and accelerated confidence interval does not include zero.