Table 1. Distribution of MIC values of SET-M33L in the collection of clinical bacterial isolates, including distribution with respect to resistance phenotypes.

Species and resistance phenotypes (no. isolates)a,b	MIC
	[μM]	0.18	0.35	0.7	1.4	2.8	5.6	11.2	>11.2
	[μg/mL]	1	2	4	8	16	32	64	>64
Pseudomonas aeruginosa (76)		0	1	8	64	2	0	1	0
MDR (32)		0	0	2	29	1	0	0	0
MDR, MBL (11)		0	0	0	11	0	0	0	0
non-MDR (44)		0	1	6	35	1	0	1	0
Klebsiella pneumoniae (73)		0	0	22	33	11	3	3	1
MDR (31)		0	0	12	10	5	1	2	1
MDR, CP, CR (6)		0	0	0	0	2	1	2	1
MDR, CP (10)		0	0	6	2	2	0	0	0
MDR, ESBL, CR (1)		0	0	0	0	1	0	0	0
MDR, ESBL (12)		0	0	4	8	0	0	0	0
non-MDR (42)		0	0	10	23	6	2	1	0
Non-MDR, ESBL (2)		0	0	0	2	0	0	0	0
	MIC50	[μM]	[μg/mL]		MIC90	[μM]	[μg/mL]
Pseudomonas aeruginosa (no. 76)		1.4	8			1.4	8
Klebsiella pneumoniae (no. 73)		1.4	8			2.8	16

^aStrains were identified according to the presence of relevant resistance phenotypes and genotypes as follows: MDR, multidrug resistant (according to the definition of Magiorakos et al.³⁹); CP, carbapenemase-producing; CR, colistin-resistant; ESBL, extended spectrum β-lactamase-producing; MBL, metallo-β-lactamase-producing.

^bBacterial strains belonging to the successful epidemic P. aeruginosa Sequence Type 621, producing the IMP-13 MBL, and K. pneumoniae Sequence Type 512, producing a KPC-type carbapenemase, were included.