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. 2015 Jul 28;67(8):2076–2084. doi: 10.1002/art.39186

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© 2015 The Authors. Arthritis & Rheumatology is published by Wiley Periodicals, Inc. on behalf of the American College of Rheumatology

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Familywise P values for all 492 tests (41 single‐nucleotide polymorphisms [SNPs], 12 statistical shape model [SSM] modes) for association between univariate SSM modes of the proximal femur and candidate SNPs. All familywise P values are before adjustment for covariates and were obtained by running 100,000 permutations. The expected level for significance was a familywise P value of less than 0.05, which is indicated by the dashed line. Three SNPs (rs6976, rs5009270, and rs4836732) reached this significance level and 1 SNP (rs12901499) was just above it. Every SNP was tested following an additive genetic model in the stratum where the original association had been found (i.e., mixed‐sex [blue], female [green], or male [red]).