Table 2.
Distribution of genotype and allele frequency in different clinical feature of cervical dystonia patients.
| Variations | rs61973742 | rs1338041 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| AA, AG, GG | P value | MAF (%) | P value | OR (95% CI) | AA, AC, CC | P value | MAF (%) | P value | OR (95% CI) | |
| Sex | ||||||||||
| Men (N = 77) | 49, 26, 2 | 0.476 | 30 (19.5) | 0.332 | 0.771 (0.456–1.304) | 16, 41, 20 | 0.295 | 73 (47.4) | 0.140 | 1.356 (0.904–2.035) |
| Female (N = 124) | 86, 37, 1 | 39 (15.7) | 20, 59, 45 | 99 (39.9) | ||||||
| Family history | ||||||||||
| Positive (N = 41) | 25, 15, 1 | 0.590 | 17 (20.7) | 0.337 | 0.742 (0.403–1.367) | 6, 18, 17 | 0.370 | 30 (36.6) | 0.203 | 0.723 (0.438–1.193) |
| Negative (N = 160) | 110, 48, 2 | 52 (16.3) | 30, 82, 48 | 142 (44.4) | ||||||
| Age at onset | ||||||||||
| <26 (N = 50) | 37, 11, 2 | 0.077 | 15 (15.0) | 0.508 | 1.234 (0.662–2.300) | 8, 26, 16 | 0.902 | 42 (42.0) | 0.854 | 0.958 (0.660–1.514) |
| >26 (N = 151) | 98, 52, 1 | 54 (17.9) | 28, 74, 49 | 130 (43.0) | ||||||
MAF: minor allele frequency; OR: odds ratio; CI: confidence interval.