. Author manuscript; available in PMC: 2017 Jan 1.

Published in final edited form as: J Bronchology Interv Pulmonol. 2016 Jan;23(1):14–21. doi: 10.1097/LBR.0000000000000246

Table 2.

Diagnostic Yield for Various DPLDs using TBLB and TBLC.

Clinical Diagnosis	TBLB and TBLC Similar and Diagnostic	TBLB Diagnostic TBLC Non-Diagnostic	TBLB Non-Diagnostic TBLC Diagnostic	Neither TBLB nor TBLC Diagnostic
ILD^*	4	0	3	3
OP	6	2	1	0
HSP	1	0	2	0
Sarcoid	1	0	1	1
Malignancy	5	0	0	0
Drug Reaction	5	1	1	0
Other^**	4	1	3	11
Total (56)	26	4	11	15^***

ILD = Interstitial lung disease; OP = organizing pneumonia; HSP = hypersensitivity pneumonitis

^**

“Other” includes both infectious and non-infectious pneumonias (n=10), normal pathology (n=3), GVHD, hemophagocytic syndrome, extramedullary hematopoiesis, cardiac amyloidosis (no pulmonary involvement), and ABPA. Although biopsies did not reveal a specific diagnosis in 11 of the “other” patients, the diagnosis was made by microbiologic data from BAL or exclusion of other diseases by bronchoscopy.

^***

Of the 15 patients without a clear diagnosis by pathology, only 2 underwent VATS to confirm a diagnosis. Others were diagnosed with bronchoscopic and clinical data.