Table 3.
Existing literature regarding use of TBLC as of June 2015.
| Authors | Date | Disease | N | Procedure | Outcome | Complications |
|---|---|---|---|---|---|---|
| Hagmeyer, et al. | 01/2015 | ILD | 32 | General anesthesia Rigid bronchoscopy |
72% definitive diagnosis | Bleeding Severe 53% Mod 25% Pneumothorax 19% |
| Griff, et al. | 11/2014 | DPLD | 52 | Flexible bronchoscopy | 79% diagnostic yield | No bleeding > 3 minutes Pneumothorax 0% |
| Hernandez-Gonzalez, et al. | 11/2014 | ILD | 33 | Flexible bronchoscope | 79% yield | Bleeding Grade 1 9% Grade 2 21% |
| Pajares, et al. | 8/2014 | ILD | 77 | Intubated for TBLC Flexible bronchoscope | TBLC yield higher than TBLB (54.1 vs 29.1%; p=0.038) | Bleeding Grade 1 30.8% Grade 2 56.5% Pneumothorax 7.7% |
| Fruchter, et al. | 7/2014 | ILD | 75 | Flexible bronchoscopy (Only TBLC performed) | 73/75 had abnormal tissue | Bleeding 4% Pneumothorax 2.6% |
| Poletti, et al. | 3/2014 | DPLD | 176 | Unclear | 80% specific pathologic pattern | Bleeding 0% Pneumothorax 23% |
| Casoni, et al. | 2/2014 | ILD | 69 | Rigid bronchoscopy | 76% specific pathologic pattern | Bleeding 1.4% Pneumothorax 28% Death (1 IPF exacerbation) |
| Fruchter, et al. | 12/2013 | Immuno-suppressed | 15 | Flexible bronchoscopy | 80% change in management | Bleeding 6.7% Pneumothorax 0% |
| Kropski, et al. | 11/2013 | DPLD | 25 | Intubated patients | 80% diagnostic yield | Bleeding 0% Pneumothorax 0% |
| Fructer, et al. | 5/2013 | Post-transplant | 40 | Flexible bronchoscopy | Improved yield over TBLB | Bleeding 2.5% Pneumothorax 0% |
| Yarmus, et al. | 3/2013 | Post-transplant | 21 | Rigid and flexible bronchoscopy | TBLC specimens larger and less artifact | Bleeding Grade 1 52.4% |
| Babiak, et al. | 08/2009 | ILD | 41 | Intubated patients Flexible bronchoscopy | Improved yield over TBLB | Bleeding 0% Pneumothorax 4.9% |
Table 3 References In Chronological Order :
1. Hagmeyer L, Theegarten D, Wohlschlager J et al. The role of transbronchial cryobiopsy and surgical lung biopsy in the diagnostic algorithm of interstitial lung disease. Clin Respir J. 2015 Jan 26
2. Griff S, Schonfeld N, Ammenwerth W et al. Diagnostic yield of transbronchial cryobiopsy in non-neoplastic lung disease: a retrospective case series. BMC Pulm Med 2014 Nov 3; 14 (1):171.
3. Hernandez-Gonzalez. Cryobiopsy in the Diagnosis of Diffuse Interstitial Lung Disease: Yield and Cost-Effectiveness Analysis. Arch Bronconeumol. 2014 Nov 3.
4. Pajares V, Puzo C, Castillo D et al. Diagnostic yield of transbronchial cryobiopsy in interstitial lung disease: a randomized trial. Respirology. 2014 Aug;19(6):900–6.
5. Fruchter O, Fridel L, El Raouf BA, et al. Histological diagnosis of interstitial lung diseases by cryo-transbronchial biopsy. Respirology. 2014 Jul;19(5):683–8.
6. Poletti V, Casoni GL, Gurioli C et al. Lung cryobiopsies: a paradigm shift in diagnostic bronchoscopy ? Respirology. 2014 Jul;19(5):645–54.
7. Casoni GL, Tomassetti S, Cavazza A et al. Transbronchial Lung Cryobiopsy in the Diagnosis of Fibrotic Interstitial Lung Diseases. PLos One. 2014 Feb 28; 9(2): e86716
8. Fruchter O, Fridel L, Rosengarten D et al. Transbronchial cryobiopsy in immunocompromised patients with pulmonary infiltrates: a pilot study. Lung 2013 Dec;191(6):619–24.
9. Kropski JA, Pritchett JM, Mason WR et al. Bronchoscopic Cryobiopsy for the Diagnosis of Diffuse Parenchymal Lung Disease. PLos One. 2013 Nov 12;8(11):e78674.
10. Fruchter O, Fridel L, Rosengarten D et al. Transbronchial cryo-biopsy in lung transplantation patients: first report. Respirology.2013 May;18(4):669–73
11. Yarmus L, Akulian J, Gilbert C et al. Cryoprobe transbronchial lung biopsy in patients after lung transplantation: a pilot safety study. Chest. 2013;143(3):621–6.
12. Babiak A, Hetzel J, Krishna G et al. Transbronchial Cryobiopsy: A New Tool for Lung Biopsies. Respiration 2009;78:203–208