Figure 3. Effects of the normal diet and FF Diet on glomerular injury in Nlrp3+/+ and Nlrp3-/- mice.
Values are arithmetic means ± SEM (n=6 each group) of urinary albumin (A) excretion in Nlrp3+/+ and Nlrp3-/- mice with or without the FF diet. B: Photomicrographs show typical glomerular structure (original magnification, ×400) in Nlrp3+/+ and Nlrp3-/- mice fed with or without FF diet, C: Summarized data of glomerular damage index (GDI) by semi-quantitation of scores in 4 different groups of mice (n=6 each group). For each kidney section, 50 glomeruli were randomly chosen for the calculation of GDI. Significant difference (P<0.05) compared to the values from control Nlrp3+/+ mice, # Significant difference (P<0.05) compared to the values from Nlrp3+/+ mice receiving the FF diet.