Figure 3. Anatomy of the commonly deleted region on 9p in LGG.
(A) Segmentation map of somatic copy number alterations (SCNAs) on chromosome 9p in the TCGA LGG cohort.
(B) Diagram of select genes within the commonly deleted region on 9p ordered by chromosomal location. Known oncogenes (red), tumor suppressor genes (blue), and mixed role genes (green) are shown, along with uncharacterized loci (black).
(C) Overview of genetic alterations at 72 loci for which copy number data is available within the 9p commonly deleted region in the TCGA LGG cohort.
LGG, lower grade glioma; Het, heterozygous deletion; HD, homozygous deletion; Mut, mutation; Amp, amplification; Chr, chromosome; LGG, lower grade glioma.