Figure 1.

Memory retrieval increases in vtiro proteasome activity and decreases GluR2 in the amygdala and increases GluR1 in the hippocampus. (a) Rats were exposed to several pairings of an auditory cue with a footshock and amygdala tissue collected 90 or 120 min later (n=10–11 per group). (b) Proteasome activity was increased 120 min after retrieval. (c) GluR1 and GluR2 levels were decreased 120 min after retrieval with no change in β-actin expression (d). Memory retrieval did not alter proteasome activity (e) but did increase GluR1 expression (f) in the hippocampus. There were no changes in β-actin expression in the hippocampus (g). *P<0.05 from no retrieval.