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. 2015 Jun 10;40(12):2832–2842. doi: 10.1038/npp.2015.133

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Copyright © 2015 American College of Neuropsychopharmacology

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Effect of insular lesions on acquisition of the rat gambling task (rGT). Rostral agranular (RAIC-) (a), but not the caudal granular (CGIC-) (b), lesioned animals demonstrated significantly different acquisition of choice behavior as compared with sham controls (c). RAIC-, but not CGIC-, lesioned animals demonstrated a significantly greater preference for optimal choices (P1+P2) compared with sham controls (d). Finally, RAIC-, but not CGIC-, lesioned animals had a significantly greater percentage of optimal responders each session on average compared with sham controls (e).