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. 2016 Apr 20;45(2):565–575. doi: 10.1093/ije/dyw040

Table 3.

Model-adjusted associations of current unpasteurized milk consumption with current atopy status 40

Model Model variables * Exposure coefficient estimate SE for coefficient OR 95% CL for OR Estimated bias and RMSE Bootstrap SE for coefficient Bootstrap 95% CL for OR
1 (basic) Milk 0.899 0.225 2.46 1.58, 3.82
  • 0.516

  • 0.567

0.236 1.59, 3.97
2a (ML full)
  • Milk

  • All other variables #

0.406 0.257 1.50 0.91, 2.48
  • 0.023

  • 0.262

0.261 0.89, 2.46
2b (Firth) 42,43
  • Milk

  • All other variables #

0.383 0.252 1.47 0.91, 2.40
  • 0.000

  • 0.251

0.251 0.89, 2.37
3a (forwards stepwise, P < 0.20)
  • Milk

  • Town

  • Firstborn

  • Current smoker

  • Town as a child

  • Parents farmers

  • Parents kept poultry

  • Parents kept horses

0.390 0.244 1.48 0.91, 2.38
  • 0.007,

  • 0.261

0.261 0.87, 2.43
3b (forwards stepwise, P < 0.05)
  • Milk

  • Town

  • Current smoker

  • Town as a child

  • Parents kept poultry

0.383 0.243 1.47 0.91, 2.36
  • <0.001

  • 0.261

0.261 0.88, 2.44
3c (backward stepwise, P < 0.20)
  • Milk

  • Town

  • Firstborn

  • Current smoker

  • Parents farmers

  • Parents kept poultry

  • Parents kept horses

0.398 0.244 1.49 0.92, 2.40
  • 0.015

  • 0.261

0.261 0.88, 2.47
3d (backward stepwise, P < 0.05)
  • Milk

  • Town

  • Current smoker

  • Parents farmers

  • Parents kept poultry

  • Parents kept horses

0.414 0.244 1.51 0.94, 2.44
  • 0.031

  • 0.265

0.263 0.93, 2.61
4a (forwards AIC)
  • Milk

  • Town

  • Horses

  • Firstborn

  • Current smoker

  • Parents kept poultry

0.381 0.243 1.46 0.91, 2.36
  • −0.002

  • 0.260

0.260 0.86, 2.39
4b (backward AIC)
  • Milk

  • Town

  • Horses

  • Firstborn

  • Current smoker

  • Parents kept poultry

  • Parents kept horses

  • Parents farmers

0.398 0.244 1.49 0.92, 2.40
  • 0.015

  • 0.262

0.262 0.88, 2.48
5a (forwards BIC)
  • Milk

  • Town

  • Current smoker

  • Parents kept poultry

0.393 0.243 1.48 0.92, 2.39
  • 0.010

  • 0.264

0.264 0.88, 2.45
5b (backward BIC)
  • Milk

  • Town

  • Current smoker

  • Parents kept poultry

0.393 0.243 1.48 0.92, 2.39
  • 0.010

  • 0.264

0.264 0.87, 2.45
6a (forwards CIE)
  • Milk

  • Town

0.400 0.242 1.49 0.93, 2.39
  • 0.017

  • 0.255

0.254 0.93, 2.56
6b (backward CIE)
  • Milk

  • Town

0.400 0.242 1.49 0.93, 2.39
  • 0.017

  • 0.255

0.254 0.92, 2.52
7a (forwards RMSE, larger model as referent)
  • Milk

  • Town

  • Poultry

  • Collecting eggs

  • Number of siblings

  • Parents kept cows

  • Parents kept poultry

0.363 0.245 1.44 0.89, 2.32
  • −0.020

  • 0.258

0.257 0.86, 2.35
7b (backward RMSE, larger model as referent)
  • Milk

  • Town

  • Poultry

  • Collecting eggs

  • Firstborn

0.350 0.243 1.42 0.88, 2.29
  • 0.017

  • 0.257

0.256 0.84, 2.28
8a (forwards RMSE, full model as referent)
  • Milk

  • Town

0.400 0.242 1.49 0.93, 2.39
  • −0.033

  • 0.263

0.261 0.88, 2.45
8b (backward RMSE, full model as referent)
  • Milk

  • Town

  • Parents kept cows

  • Parents kept poultry

0.407 0.242 1.50 0.94, 2.42
  • 0.024

  • 0.264

0.263 0.89, 2.51
9a penalization by log-F(1,1) priors §45
  • Milk

  • All other variables #

0.396 0.253 1.49 0.90, 2.44
  • 0.013

  • 0.253

0.253 0.90, 2.42
9b penalization by log-F(2,2) priors 45
  • Milk

  • All other variables #

0.389 0.250 1.47 0.90, 2.41
  • 0.006

  • 0.246

0.246 0.90, 2.36

*All analyses are adjusted for age group and sex.

Based on 4000 bootstrap samples.

Bias-corrected and accelerated (BCa) with 4000 resamples. 56

# Town, farm, cows, pigs, poultry, sheep/goats, horses, milking cows, cleaning barns, collecting eggs, firstborn, number of siblings, current smoker, lived in town or village as a child, parents were farmers, family kept cows, family kept pigs, family kept poultry, family kept sheep or goats, family kept horses.

§ Equivalent to F(1,1) prior for odds ratio; 95% prior limits are 1/648, 648.

Equivalent to F(2,2) prior for odds ratio; 95% prior limits are 1/39, 39.