Table 2.
Risk factor | Crude* OR |
Adjusted† OR (95% CI) |
Fully Adjusted§ OR (95% CI) |
---|---|---|---|
Age, years | |||
50 to 55 | ref | ref | ref |
56 to 63 | 0.95 | 0.96 (0.53, 1.72) | 1.03 (0.55, 1.91) |
64 to 79 | 1.03 | 1.12 (0.62, 2.02) | 1.08 (0.57, 2.05) |
Gender | |||
male | ref | ref | ref |
female | 0.71 | 0.70 (0.43, 1.15) | 0.80 (0.46, 1.40) |
Body mass index, kg/m2 | |||
<25 | ref | ref | ref |
25 to 29 | 0.99 | 0.94 (0.43, 2.02) | 0.96 (0.44, 2.09) |
30 or above | 1.69 | 1.62 (0.79, 3.33) | 1.52 (0.73, 3.16) |
Bony enlargements of finger joints‡, n | |||
0 to 4 | ref | ref | ref |
5 or more | 1.61 | 1.66 (1.03, 2.68) | 1.64 (1.00, 2.70) |
Knee injury during follow-up** | |||
no | ref | ref | ref |
yes | 4.84 | 4.67 (2.31, 9.42) | 4.14 (2.06, 8.31) |
Knee alignment | |||
not varus (≥179°) | ref | ref | ref |
varus (<179°) | 2.20 | 2.09 (1.24, 3.51) | 2.00 (1.18, 3.40) |
Leg-length inequality | |||
less than 1 cm | ref | ref | ref |
1 cm or more | 0.84 | 0.80 (0.40, 1.61) | 0. 90 (0.45, 1.80) |
OR= odds ratio, 95% CI=95% confidence interval, ref = reference category
Adjusted for race and clinical site only (generalised estimating equations).
Adjusted for race, clinical site, age, sex, and body mass index only (generalised estimating equations).
The primary model, adjusted for all covariates in the table and race and clinical site (generalised estimating equations).
Test for trend using continuous predictor variable, P=0.28.
Knee injury leading to limited ability to walk for 2 days or more.