Table 1.
Baseline characteristics among CKD risk grades in the general population
| Total (n = 22,975) | eGFR + Dipstick | P valuesa | eGFR + UACR | P valuesa | |||||
|---|---|---|---|---|---|---|---|---|---|
| Grade 1 (20,902) | Grade 2 (1,462) | Grade 3 & 4 (611) | Grade 1 (16,376) | Grade 2 (5,630) | Grade 3 & 4 (969) | ||||
| Age(year) | 62.9 ± 10.0 | 62.2 ± 9.8 | 70.6 ± 8.7 | 69.7 ± 9.1 | < 0.001 | 61.3 ± 9.8 | 66.3 ± 9.3 | 70.6 ± 8.4 | < 0.001 |
| Male | 34.1 % | 32.9 % | 45.3 % | 49.8 % | < 0.001 | 33.9 % | 33.2 % | 43.9 % | < 0.001 |
| BMI(kg/m 2 ) | 24.0 ± 3.3 | 24.0 ± 3.2 | 24.3 ± 3.4 | 25.1 ± 3.6 | < 0.001 | 23.8 ± 3.1 | 24.6 ± 3.5 | 25.0 ± 3.6 | < 0.001 |
| Hypertension | 41.5 % | 39.4 % | 58.1 % | 72.7 % | < 0.001 | 34.4 % | 59.6 % | 72.5 % | < 0.001 |
| Diabetes Mellitus | 6.6 % | 6.1 % | 8.9 % | 19.0 % | < 0.001 | 4.9 % | 9.9 % | 16.1 % | < 0.001 |
| Dyslipidemia | 16.4 % | 16.2 % | 18.0 % | 18.8 % | 0.052 | 15.7 % | 17.7 % | 20.3 % | 0.052 |
| Current Smoking | 12.0 % | 12.0 % | 11.6 % | 14.1 % | 0.246 | 12.3 % | 11.0 % | 12.1 % | 0.246 |
| Atrial Fibrillation | 1.4 % | 1.1 % | 3.8 % | 5.7 % | < 0.001 | 0.8 % | 2.6 % | 5.2 % | < 0.001 |
| UACb < 30 | 75.5 % | 79.0 % | 52.1 % | 10.8 % | < 0.001 | 100 % | 14.1 % | 6.4 % | < 0.001 |
| UAC 30-300 | 22.7 % | 20.9 % | 42.5 % | 39.4 % | 0 % | 85.9 % | 45.2 % | ||
| UAC > 300 | 1.8 % | 0.1 % | 5.4 % | 49.8 % | 0 % | 0 % | 48.4 % | ||
| Proteinuria (dip stick) | |||||||||
| - Negative (−) | 96.4 % | 100 % | 75.4 % | 21.9 % | < 0.001 | 99.8 % | 93.7 % | 53.7 % | < 0.001 |
| - Trace (+/−) | 1.8 % | 0 | 24.6 % | 9.7 % | 0.2 % | 4.5 % | 14.2 % | ||
| - Positive (≥ +) | 1.8 % | 0 | 0 | 68.4 % | 0 | 1.8 % | 32.1 % | ||
| eGFR(mL/min/1.73m 2 ) | 76.8 ± 10.1 | 78.5 ± 7.8 | 60.3 ± 10.8 | 58.8 ± 18.9 | < 0.001 | 78.8 ± 7.9 | 74.2 ± 10.7 | 58.7 ± 16.2 | < 0.001 |
| Number of the Events | |||||||||
| - AMI | 145 | 109 | 22 | 15 | < 0.001 | 75 | 51 | 20 | < 0.001 |
| - Stroke | 563 | 455 | 65 | 42 | < 0.001 | 286 | 215 | 61 | < 0.001 |
| - Composite event | 708 | 564 | 87 | 57 | < 0.001 | 361 | 266 | 81 | < 0.001 |
a Differences among the CKD grades
b Urine Albumin Creatinine Ratio