Table 4. Effects of DMG-Na on mitochondrial antioxidant system in LPS-injected mice liver 1.
Treatment 3 | ||||
---|---|---|---|---|
Item 2 | CS | CL | DS | DL |
MnSOD (U/mg protein) | 98.04±1.25b | 41.05±1.07d | 112.18±2.31a | 78.53±1.20c |
GSH (U/mg protein) | 0.44±0.03b | 0.25±0.02c | 0.71±0.04a | 0.38±0.02b |
GPx (U/mg protein) | 49.60±0.19b | 21.35±0.14d | 55.17±0.25a | 28.06±0.25c |
GR (U/mg protein) | 2.91±0.09b | 0.73±0.02d | 3.18±0.05a | 1.36±0.06c |
a-d Means in the same row with different superscripts differ (P < 0.05).
1 CS, gastric intubation in mice with 0 mg DMG-Na/0.3 ml sterile saline solution for 28 days and intraperitoneal injection with 100 μg/kg body weight of sterile saline solution at 29 day; CL, gastric intubation in mice with 0 mg DMG-Na/0.3 ml sterile saline solution for 28 days and intraperitoneal injection with 100 μg/kg body weight of LPS at 29 day; DS, gastric intubation in mice with 12 mg DMG-Na/0.3 ml sterile saline solution for 28 days and intraperitoneal injection with 100 μg/kg body weight of sterile saline solution at 29 day; DL, gastric intubation in mice with 12 mg DMG-Na/0.3 ml sterile saline solution for 28 days and intraperitoneal injection with 100 μg/kg body weight of LPS at 29 day.
2 Manganese superoxide dismutase (MnSOD), Glutathione (GSH), Glutathione peroxidase (GPx), Glutathione reductase (GR).
3 Each mean represents one replicate pens with 10 mice per pen.