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. 2016 May 12;11(5):e0154984. doi: 10.1371/journal.pone.0154984

Fig 5. Progressive degeneration of hair bundles in Tur/Tur cochleae.

Fig 5

(A,B) Immunofluorescence of anti-myosin VI on cochlear sections of wild-type (A) and Tur/Tur mutant at P0 (from middle turn). Arrow points to smaller tunnel of Corti in the mutant. (C-D) Phalloidin staining of whole-mount cochlear sensory epithelium (middle turn) from P0 (C,D), P14 (E,F) and P21 (G,H) with phalloidin (red). Myo6Tur/Tur cochleae show irregular shapes of hair bundles compared to wild-type cochleae throughout all regions of the cochlea. Asterisks in H point to degeneration or elongation of stereocilial bundles in the mutant at P21. IHC, inner hair cell; OHC, outer hair cell. Scale bar: 25 μm.